Great question!

Dear Sexperts,

Is it normal to feel depressed or very moody if you don’t have sex for two days? Is there an effect on the brain?

Answer:

Depression as a result of not having sex can be attributed to several causes. Sometimes, in a relationship, a lack of sex can be a sign of a much larger problem that is causing you to be unhappy with or about your partner. If you are not engaging in sexual activity because of a fight or problem, it may be that your depression is a result of that troubling incident, and not specifically the lack of sex. There is also research that suggests that orgasms can increase the amounts of serotonin in your body, which would lead to a feeling of euphoria or total happiness. Less sex can lead to less happiness. It is important that sex makes you happy; however, you do not want to be dependent on sex as the only thing that makes you feel good. The hormones that are released in your brain as a result of orgasm are only a temporary solution if you are experiencing severe depression. If you feel that the only time you are not depressed is when you are sexually engaged, it may be helpful for you to confront your depression rather than increase the amount of sex that you are having. After prolonged depression, many people consult with a physician.

Sincerely,
The Sexperts